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Query: ARPC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARPC3 0 0.015 0.220 -0.170 -0.040 0.697 -0.078
ARPC3 0 0.015 1.270 -0.690 -0.040 0.697 -0.078

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARPC3 Ubiquitylation K123 -0.335 -0.564 _PANK(gl)QEDEVMR_
ARPC3 Ubiquitylation K147 -1.055 _LCEK(gl)VFDPQNDKPSK_
ARPC3 Ubiquitylation K29 -2.547 -1.252 _SQFK(gl)GPAPR_
ARPC3 Ubiquitylation K171 -1.371 _QFMNK(gl)SLSGPGQ_

Background Information for ARPC3:


Pubmed-ARPC3 »
Uniprot-ARPC3 »
Biogrid-ARPC3 »
ProteomicsDB-ARPC3 »

Tumorportal-ARPC3 »
COSMIC-ARPC3 »
GenomeRNAi-ARPC3 »
Genecards-ARPC3


Protein-protein Interactions for ARPC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1430 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTMS Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARPC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARPC3
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ARPC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 27 Arp2/3 protein complex Database 0.04


Categories featuring ARPC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_615 BIOCARTA_CDC42RAC_PATHWAY 0 0.18
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_236 BIOCARTA_MPR_PATHWAY 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0034314 Arp2/3 complex-mediated actin nucleation Database 0.01
Category members Pathway Pathway_1037 BIOCARTA_SALMONELLA_PATHWAY 0 0
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005885 Arp2/3 protein complex Database 0
Category members GO Category GO:0030833 regulation of actin filament polymerization Database 0


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