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Query: ARPC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARPC2 0 3.033 0.030 -0.550 0.168 0.850 0.629 0.392

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARPC2 Ubiquitylation K295 0.574 0.405 _TITGK(gl)TFSSR_
ARPC2 Ubiquitylation K117 -0.238 _DSIVHQAGMLK(gl)R_
ARPC2 Ubiquitylation K269 -0.631 _AK(gl)TSDFLK_
ARPC2 Ubiquitylation K290 0.589 _EMK(gl)TITGK_

Background Information for ARPC2:


Pubmed-ARPC2 »
Uniprot-ARPC2 »
Biogrid-ARPC2 »
ProteomicsDB-ARPC2 »

Tumorportal-ARPC2 »
COSMIC-ARPC2 »
GenomeRNAi-ARPC2 »
Genecards-ARPC2


Protein-protein Interactions for ARPC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait NDC80 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARPC2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ARPC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 27 Arp2/3 protein complex Database 0.04


Categories featuring ARPC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0030838 positive regulation of actin filament polymerization Database 0.21
Category members Pathway Pathway_615 BIOCARTA_CDC42RAC_PATHWAY 0 0.18
Category members GO Category GO:0035650 AP-1 adaptor complex binding Database 0.15
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_236 BIOCARTA_MPR_PATHWAY 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members Pathway Pathway_1037 BIOCARTA_SALMONELLA_PATHWAY 0 0
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005885 Arp2/3 protein complex Database 0
Category members GO Category GO:0030833 regulation of actin filament polymerization Database 0
Category members GO Category GO:0042995 cell projection Database 0


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