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Query: ARIH2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARIH2 0 3.444 -1.230 1.330 0.382

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARIH2 Ubiquitylation K259 0.706 1.026 _CNEVFCFK(gl)CR_
ARIH2 Ubiquitylation K344 0.292 0.031 _YK(gl)ENPDIVNQSQQAQAR_
ARIH2 Ubiquitylation K279 0.067 _WLTK(gl)CADDSETANYISAHTK_
ARIH2 Ubiquitylation K299 0.255 _DCPK(gl)CNICIEK_
ARIH2 Ubiquitylation K392 0.460 _IHEK(gl)IQER_
ARIH2 Ubiquitylation K488 0.370 _TLLK(gl)DFHDT_

Background Information for ARIH2:


Pubmed-ARIH2 »
Uniprot-ARIH2 »
Biogrid-ARIH2 »
ProteomicsDB-ARIH2 »

Tumorportal-ARIH2 »
COSMIC-ARIH2 »
GenomeRNAi-ARIH2 »
Genecards-ARIH2


Protein-protein Interactions for ARIH2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BMX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOCS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARIH2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members Znf_C6HC IPR002867 0


Protein complexes (CORUM database) featuring ARIH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARIH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0048588 developmental cell growth Database 0
Category members GO Category GO:0070534 protein K63-linked ubiquitination Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0
Category members GO Category GO:0071425 hematopoietic stem cell proliferation Database 0


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