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Query: ARHGEF10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGEF10 1 3.998 0.730 -0.720 0.021

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGEF10 Phosphorylation S379 3.977 _TKS(ph)LIAQDHR_

Background Information for ARHGEF10:


Pubmed-ARHGEF10 »
Uniprot-ARHGEF10 »
Biogrid-ARHGEF10 »
ProteomicsDB-ARHGEF10 »

Tumorportal-ARHGEF10 »
COSMIC-ARHGEF10 »
GenomeRNAi-ARHGEF10 »
Genecards-ARHGEF10


Protein-protein Interactions for ARHGEF10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGEF10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSBP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGEF10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members DH-domain IPR000219 0.05


Protein complexes (CORUM database) featuring ARHGEF10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARHGEF10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_240 BIOCARTA_PAR1_PATHWAY 0 1.11
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_677 BIOCARTA_MYOSIN_PATHWAY 0 0.53
Category members GO Category GO:0022011 myelination in peripheral nervous system Database 0.33
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members GO Category GO:0051298 centrosome duplication Database 0
Category members GO Category GO:0051496 positive regulation of stress fiber assembly Database 0


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