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Query: AKAP12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKAP12 1 3.121 0.080 0.450
AKAP12 1 3.121 0.080 0.450 -0.778 -0.718 0.001

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKAP12 Phosphorylation T1264 2.342 _TEGT(ph)QEADQYADEK_
AKAP12 Phosphorylation T1760 2.212 _VHSESDKAIT(ph)PQAQEELQK_
AKAP12 Phosphorylation S644 0.998 _SATLS(ph)STESTASEMQEEMK_
AKAP12 Phosphorylation T597 0.710 0.917 _GLAEVQQDGEAEEGAT(ph)SDGEKK_
AKAP12 Phosphorylation S15 0.751 0.906 _DSEDVSERDS(ph)DKEMATK_
AKAP12 Phosphorylation T285 0.469 0.841 _SAESPT(ph)SPVTSETGSTFKK_
AKAP12 Phosphorylation S627 0.838 _RPS(ph)ESDKEDELDK_
AKAP12 Phosphorylation S483 1.030 0.794 _ETCVSGEDPTQGADLS(ph)PDEK_
AKAP12 Phosphorylation S598 0.581 0.596 _GLAEVQQDGEAEEGATS(ph)DGEK_
AKAP12 Phosphorylation S286 1.091 0.546 _SAESPTS(ph)PVTSETGSTFK_
AKAP12 Phosphorylation S612 0.508 _REGVTPWAS(ph)FKK_
AKAP12 Phosphorylation T1116 0.039 0.415 _VVGQTT(ph)PESFEK_
AKAP12 Phosphorylation S1331 -0.306 -0.035 _SPPS(ph)PVER_
AKAP12 Phosphorylation S283 0.097 -0.169 _SAES(ph)PTSPVTSETGSTFK_
AKAP12 Phosphorylation S371 -0.434 -0.247 _LTASEQAHPQEPAESAHEPRLS(ph)AEYEK_
AKAP12 Phosphorylation S1395 -0.549 -0.627 _EVSSLEGS(ph)PPPCLGQEEAVCTK_
AKAP12 Ubiquitylation K177 0.190 _VFK(gl)FVGFK_
AKAP12 Ubiquitylation K298 -0.299 _SAESPTSPVTSETGSTFKK(gl)_
AKAP12 Ubiquitylation K875 0.733 _SAEQPEQK(gl)AATEVSK_
AKAP12 Phosphorylation S1328 0.020 _S(ph)PPSPVER_
AKAP12 Phosphorylation S1391 -0.484 _EVSS(ph)LEGSPPPCLGQEEAVCTK_

Background Information for AKAP12:


Pubmed-AKAP12 »
Uniprot-AKAP12 »
Biogrid-AKAP12 »
ProteomicsDB-AKAP12 »

Tumorportal-AKAP12 »
COSMIC-AKAP12 »
GenomeRNAi-AKAP12 »
Genecards-AKAP12


Protein-protein Interactions for AKAP12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMOT Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3B Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015


Protein Domains in AKAP12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RII_binding_1 IPR018459 0.12
Category members Pkinase-A_anch_WSK-motif IPR001573 0.04


Protein complexes (CORUM database) featuring AKAP12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 518 AKAP250-PKA-PDE4D complex Database 0.17
Category members Corum 621 AKAP250-PKA-PDE4D complex Database 0.17


Categories featuring AKAP12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0006605 protein targeting Database 0.29
Category members GO Category GO:0030819 positive regulation of cAMP biosynthetic process Database 0.04
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008179 adenylate cyclase binding Database 0
Category members GO Category GO:0010739 positive regulation of protein kinase A signaling Database 0
Category members GO Category GO:0051018 protein kinase A binding Database 0


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