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Query: ACTA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACTA2 0 -0.041 0.840 -0.100 -0.189 0.025 -0.002 -0.165
ACTA2 0 -0.041 0.840 -0.100 0.034 -0.068
ACTA2 0 -0.041 0.840 -0.100 0.157

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ACTA2:


Pubmed-ACTA2 »
Uniprot-ACTA2 »
Biogrid-ACTA2 »
ProteomicsDB-ACTA2 »

Tumorportal-ACTA2 »
COSMIC-ACTA2 »
GenomeRNAi-ACTA2 »
Genecards-ACTA2


Protein-protein Interactions for ACTA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ADAM21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AFM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BUB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPNS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CENPC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPLX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHCR24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GM2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP1LC3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MUC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHACTR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNMA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1R1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REG3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNASE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF217 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCMH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP11L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM220 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TREX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TWF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZMAT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZMAT5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF433 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACTA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Actin-related IPR004000 0.11


Protein complexes (CORUM database) featuring ACTA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 486 WIP-WASp-actin-myosin-IIa complex Database 0.31


Categories featuring ACTA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008217 regulation of blood pressure Database 0.09
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members Pathway Pathway_949 REACTOME_SMOOTH_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_950 REACTOME_MUSCLE_CONTRACTION 0 0
Category members Disease phenotype Familial_thoracic_aortic_aneurysm_and_aortic_dissection Familial thoracic aortic aneurysm and aortic dissection Database 0
Category members Disease phenotype Moyamoya_disease Moyamoya disease Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0014829 vascular smooth muscle contraction Database 0
Category members GO Category GO:0030485 smooth muscle contractile fiber Database 0


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