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Query: ABCC4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCC4 0 -0.867 0.100 -0.440 0.365 0.118

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCC4 Ubiquitylation K309 0.374 _EISK(gl)ILR_
ABCC4 Ubiquitylation K264 -2.022 0.318 _SK(gl)TATFTDAR_
ABCC4 Ubiquitylation K614 -0.015 _MVQK(gl)GTYTEFLK_
ABCC4 Ubiquitylation K77 -0.160 _AENDAQK(gl)PSLTR_
ABCC4 Ubiquitylation K540 -0.750 _GTTLSGGQK(gl)AR_
ABCC4 Phosphorylation T646 -1.005 -1.229 _DNEESEQPPVPGT(ph)PTLR_
ABCC4 Ubiquitylation K515 -1.211 _K(gl)DLQLLEDGDLTVIGDR_
ABCC4 Ubiquitylation K1218 0.159 _TDELIQKK(gl)_
ABCC4 Ubiquitylation K1278 0.511 _MVQQLGK(gl)AEAAALTETAK_

Background Information for ABCC4:


Pubmed-ABCC4 »
Uniprot-ABCC4 »
Biogrid-ABCC4 »
ProteomicsDB-ABCC4 »

Tumorportal-ABCC4 »
COSMIC-ABCC4 »
GenomeRNAi-ABCC4 »
Genecards-ABCC4


Protein-protein Interactions for ABCC4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDZK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC4A8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM128 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABCC4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members ABC_transptr_TM_dom IPR001140 0.06
Category members CysFib_conduc_TM IPR009147 0


Protein complexes (CORUM database) featuring ABCC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity Database 0.3
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0031088 platelet dense granule membrane Database 0.12
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_55 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ 0 0
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0002576 platelet degranulation Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008150 biological_process Database 0


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