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Query: ABCC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCC1 0 3.016 -0.460 -0.090 0.658 0.564

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCC1 Ubiquitylation K496 0.997 0.886 _TYQVAHM(ox)K(gl)SK_
ABCC1 Ubiquitylation K498 0.966 0.810 _TYQVAHMKSK(gl)_
ABCC1 Ubiquitylation K1181 0.241 _FIHQSDLK(gl)VDENQK_
ABCC1 Ubiquitylation K1333 0.060 _TGAGK(gl)SSLTLGLFR_
ABCC1 Ubiquitylation K908 0.598 -0.029 _QMENGMLVTDSAGK(gl)QLQR_
ABCC1 Ubiquitylation K636 -0.047 _RPVK(gl)DGGGTNSITVR_
ABCC1 Ubiquitylation K280 -0.709 -0.318 _VVYSSK(gl)DPAQPK_
ABCC1 Ubiquitylation K274 -1.486 _KQPVK(gl)VVYSSKDPAQPK_
ABCC1 Ubiquitylation K940 0.462 _AEAK(gl)KEETWK_

Background Information for ABCC1:


Pubmed-ABCC1 »
Uniprot-ABCC1 »
Biogrid-ABCC1 »
ProteomicsDB-ABCC1 »

Tumorportal-ABCC1 »
COSMIC-ABCC1 »
GenomeRNAi-ABCC1 »
Genecards-ABCC1


Protein-protein Interactions for ABCC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABCC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members ABC_transptr_TM_dom IPR001140 0.06
Category members Multidrug-R_assoc IPR005292 0


Protein complexes (CORUM database) featuring ABCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_736 PID_S1P_META_PATHWAY 0 0.73
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_683 PID_S1P_S1P1_PATHWAY 0 0
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0006691 leukotriene metabolic process Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0009235 cobalamin metabolic process Database 0
Category members GO Category GO:0019369 arachidonic acid metabolic process Database 0


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