Results for the Category
REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION
(Pathway_1120)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
MAPK14 | 2 | -0.160 | -0.350 | |||||
TAB3 | 2 | -0.550 | 1.560 | 0.022 | -0.207 | |||
TAB3 | 2 | -0.550 | 1.560 | |||||
TAB1 | 1 | 1.890 | -0.670 | |||||
TAB1 | 1 | 1.890 | -0.670 | 1.657 | ||||
RIPK2 | 1 | -1.740 | 3.580 | |||||
MAP2K3 | 0 | 0.780 | -0.600 | |||||
TAB2 | 0 | -0.030 | -0.580 | |||||
MAP2K6 | 0 | 1.270 | -0.780 | |||||
MAP3K7 | 0 | -1.120 | 1.140 | -1.048 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
MAP2K3 | Ubiquitylation | K84 | 0.045 | -0.277 | _GAYGVVEK(gl)VR_ |
MAP2K3 | Ubiquitylation | K232 | -1.394 | _TMDAGCK(gl)PYMAPER_ | |
MAP2K3 | Ubiquitylation | K247 | 0.065 | -0.737 | _INPELNQK(gl)GYNVK_ |
MAP2K6 | Phosphorylation | T28 | -1.813 | -0.792 | _EAFEQPQTSST(ph)PPRDLDSK_ |
MAP2K6 | Ubiquitylation | K232 | 0.220 | _INPELNQK(gl)GYSVK_ | |
MAP3K7 | Phosphorylation | S374 | 0.149 | -0.337 | _GS(ph)SVESLPPTSEGK_ |
MAP3K7 | Phosphorylation | S375 | 0.171 | -0.087 | _GSS(ph)VESLPPTSEGK_ |
MAP3K7 | Phosphorylation | S389 | 1.072 | 1.445 | _RMS(ph)ADMSEIEAR_ |
MAP3K7 | Phosphorylation | S439 | 0.246 | 0.198 | _S(ph)IQDLTVTGTEPGQVSSR_ |
MAP3K7 | Ubiquitylation | K474 | -0.385 | -0.242 | _MITTSGPTSEK(gl)PTR_ |
MAP3K7 | Ubiquitylation | K589 | -0.104 | _SLSTYYQQCK(gl)K_ | |
MAP3K7 | Ubiquitylation | K590 | -0.551 | 0.560 | _K(gl)QLEVIR_ |
MAPK14 | Phosphorylation | S2 | 3.221 | 3.623 | _(ac)S(ph)QERPTFYR_ |
MAPK14 | Phosphorylation | T180 | 0.958 | 1.087 | _HTDDEM(ox)T(ph)GYVATR_ |
MAPK14 | Phosphorylation | Y182 | 1.388 | 1.374 | _HTDDEM(ox)TGY(ph)VATR_ |
MAPK14 | Ubiquitylation | K249 | 0.073 | -1.380 | _LVGTPGAELLKK(gl)_ |
RIPK2 | Ubiquitylation | K410 | -2.810 | _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_ | |
RIPK2 | Phosphorylation | S531 | 0.884 | 0.839 | _SPS(ph)LNLLQNK_ |
RIPK2 | Ubiquitylation | K538 | -2.659 | _SPSLNLLQNK(gl)SM_ | |
TAB1 | Phosphorylation | S7 | -0.170 | 0.140 | _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_ |
TAB1 | Phosphorylation | S16 | -0.138 | 0.069 | _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_ |
TAB1 | Ubiquitylation | K186 | -1.015 | _SYSADGK(gl)GTESHPPEDSWLK_ | |
TAB1 | Ubiquitylation | K371 | 0.032 | _LSQLGLDAGK(gl)IK_ | |
TAB1 | Ubiquitylation | K373 | -0.007 | _LSQLGLDAGKIK(gl)_ | |
TAB2 | Phosphorylation | S580 | -0.075 | _S(ph)NSISQIPSLEEMQQLR_ | |
TAB2 | Phosphorylation | S582 | 0.331 | _SNS(ph)ISQIPSLEEMQQLR_ | |
TAB2 | Ubiquitylation | K653 | -0.519 | -0.200 | _SIIK(gl)TPK_ |
TAB3 | Phosphorylation | S4 | 3.009 | 1.852 | _(ac)AQS(ph)SPQLDIQVLHDLR_ |
TAB3 | Phosphorylation | S5 | 3.009 | 1.852 | _(ac)AQS(ph)SPQLDIQVLHDLR_ |
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