Results for the Category
Frontotemporal dementia with motor neuron disease
(Frontotemporal_dementia_with_motor_neuron_disease)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| FUS | 0 | -0.360 | 0.760 | -0.267 | -1.116 | 0.302 | ||
| TARDBP | 0 | -1.050 | 1.160 | -0.359 | -1.276 | -0.495 | -0.408 | 0.021 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| FUS | Ubiquitylation | K319 | 0.572 | _K(gl)TGQPMINLYTDR_ | |
| TARDBP | Ubiquitylation | K95 | 0.123 | _KMDETDASSAVK(gl)VK_ | |
| TARDBP | Ubiquitylation | K145 | 0.090 | _TGHSK(gl)GFGFVR_ | |
| TARDBP | Ubiquitylation | K160 | 0.720 | _FTEYETQVK(gl)VMSQR_ | |
| TARDBP | Ubiquitylation | K176 | -0.001 | 0.145 | _WCDCK(gl)LPNSK_ |
| TARDBP | Ubiquitylation | K181 | -0.479 | -0.804 | _LPNSK(gl)QSQDEPLR_ |
| TARDBP | Ubiquitylation | K263 | 0.619 | _GISVHISNAEPK(gl)HNSNR_ |
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