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bioLOGIC CategoryView

bioLOGIC CategoryView



This section displays our screening results in the context of biological categories, such as pathways, disease-associated genes, and CORUM protein complexes

Please select first a Category type and then an individual category from the selection menu below.

Svestrup lab categories are categories assembled by the Svejstrup lab. Pathways are gene collections taken from the Reactome and KEGG databases. The menu Human Mutations are groups of disease-associated genes taken from the articles listed in that sub-selection. Disease phenotypes lists groups of genes associated with a particular disease. The Interpro sub-selection lists groups of genes associated with a particular Interpro domain. The CORUM sub-selection lists (biochemical) protein complexes curated in the CORUM database. The sub-selection DNA Damage Literature lists gene selections that have been highlighted by individual articles in the DNA damage literature.




Please select the category type to display by selecting one of the
Category Types:
Svejstrup Lab | Pathways | Human Mutations | Disease Phenotype | Interpro | CORUM | DNA Damage Literature
Show screen data for Category Id Category Name and Description Category Type TC-NER relevance -log10(p-value)
Category members Sanger cancer genes Sanger cancer genes Human mutations 4.88
Category members Broad cancer genes Broad cancer genes (Lawrence et al., 2014) Human mutations 1.14
Category members pubmedid:24460190 The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia (Bastian, 2014). Human mutations 0.88
Category members pubmedid:22817889 A Landscape of Driver Mutations in Melanoma (Hodis et al, Cell 2012) Human mutations 0.15
Category members pubmedid:22197930 Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing (Stark et al, Nat.Genet. 2011) Human mutations 0
Category members pubmedid:22197931 Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma (Nikolaev Nat. Genet. 2011). Human mutations 0
Category members pubmedid:22842228 Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. (Krauthammer et al, Nat. Genet. 2012 Human mutations 0


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