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BIOCARTA_LONGEVITY_PATHWAY
(Pathway_450)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
FOXO3 2 -0.410 -0.120
CAT 2 2.260 -1.180 1.895 -0.238
SOD2 1 -0.340 0.140 2.161 -0.330
IGF1R 1 -0.490 0.750 1.476 0.714
PIK3CA 0
SOD1 0 1.450 -1.250
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PIK3R1 0 1.910 -1.220 -0.441 0.147
HRAS 0 1.470 -0.520

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
FOXO3 Phosphorylation S12 -1.324 _(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3 Phosphorylation S253 2.510 _AVS(ph)MDNSNKYTK_
FOXO3 Phosphorylation S284 4.138 6.011 _AALQTAPESADDS(ph)PSQLSK_
FOXO3 Phosphorylation S421 1.295 _GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3 Phosphorylation S425 1.471 _GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
IGF1R Ubiquitylation K47 1.146 _NDYQQLK(gl)R_
IGF1R Ubiquitylation K1033 5.779 _VAIK(gl)TVNEAASMR_
IGF1R Ubiquitylation K1168 0.191 _K(gl)GGKGLLPVR_
IGF1R Ubiquitylation K1171 0.232 _GGK(gl)GLLPVR_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
SOD1 Ubiquitylation K4 -0.329 _(ac)ATK(gl)AVCVLK_
SOD1 Ubiquitylation K10 0.211 0.582 _AVCVLK(gl)GDGPVQGIINFEQK_
SOD1 Ubiquitylation K24 -0.435 -0.086 _GDGPVQGIINFEQK(gl)ESNGPVK_
SOD1 Ubiquitylation K31 -0.109 0.332 _ESNGPVK(gl)VWGSIK_
SOD1 Phosphorylation S99 0.405 _HVGDLGNVTADKDGVADVS(ph)IEDSVISLSGDHCIIGR_
SOD1 Ubiquitylation K123 0.352 0.004 _TLVVHEK(gl)ADDLGK_
SOD1 Ubiquitylation K129 0.143 _ADDLGK(gl)GGNEESTK_
SOD1 Ubiquitylation K137 0.464 0.934 _ADDLGKGGNEESTK(gl)TGNAGSR_


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