bioLOGIC Category
Results for the Category
Megalencephaly - polymicrogyria - post-axial polydactyly - hydrocephalus
(Megalencephaly_-_polymicrogyria_-_post-axial_polydactyly_-_hydrocephalus)
RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
W |
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|
Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
AKT3
|
2
|
0.580
|
-0.030
|
-0.194
|
|
|
|
|
AKT3
|
2
|
0.580
|
-0.030
|
|
|
|
|
|
PIK3R2
|
1
|
2.740
|
-1.180
|
|
|
|
0.269
|
0.348
|
CCND2
|
1
|
1.210
|
-0.610
|
|
|
|
|
|
Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
AKT3
|
Ubiquitylation
|
K14
|
0.306
|
0.070
|
_EGWLHK(gl)R_
|
AKT3
|
Ubiquitylation
|
K14
|
4.941
|
5.277
|
_EGWVQK(gl)R_
|
AKT3
|
Ubiquitylation
|
K111
|
1.082
|
|
_AIQMVANSLK(gl)QR_
|
AKT3
|
Phosphorylation
|
S120
|
|
1.097
|
_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
|
AKT3
|
Ubiquitylation
|
K160
|
|
0.251
|
_LLGK(gl)GTFGK_
|
AKT3
|
Phosphorylation
|
T451
|
-0.091
|
-0.612
|
_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
|
AKT3
|
Phosphorylation
|
Y456
|
|
-0.265
|
_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
|
CCND2
|
Ubiquitylation
|
K45
|
-0.759
|
-0.277
|
_YLPQCSYFK(gl)CVQK_
|
CCND2
|
Ubiquitylation
|
K49
|
|
-0.524
|
_CVQK(gl)DIQPYMR_
|
CCND2
|
Ubiquitylation
|
K113
|
|
-0.572
|
_LK(gl)ETSPLTAEK_
|
CCND2
|
Ubiquitylation
|
K173
|
-1.137
|
0.202
|
_EK(gl)LSLIR_
|
CCND2
|
Phosphorylation
|
S269
|
|
0.049
|
_DGS(ph)KSEDELDQASTPTDVR_
|
CCND2
|
Phosphorylation
|
S271
|
|
2.155
|
_DGSKS(ph)EDELDQASTPTDVR_
|
PIK3R2
|
Phosphorylation
|
S262
|
|
-2.237
|
_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
|
PIK3R2
|
Phosphorylation
|
S263
|
|
-2.237
|
_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
|
PIK3R2
|
Ubiquitylation
|
K500
|
-0.189
|
|
_IFEEQGQTQEK(gl)CSK_
|
PIK3R2
|
Ubiquitylation
|
K541
|
-0.609
|
|
_TK(gl)LEQQLR_
|
PIK3R2
|
Ubiquitylation
|
K564
|
-0.431
|
-1.022
|
_MNSLK(gl)PDLMQLR_
|
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