bioLOGIC Category
Results for the Category
LAT-PLC-gamma-1-p85-GRB2-SOS signaling complex, C305 activated
(2922)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
PLCG1
|
1
|
-0.170
|
0.000
|
|
|
|
|
|
|
SOS1
|
0
|
0.500
|
-0.620
|
-0.570
|
|
|
|
|
|
PIK3R1
|
0
|
1.910
|
-1.220
|
|
|
|
-0.441
|
0.147
|
|
GRB2
|
0
|
-0.240
|
0.300
|
|
-1.021
|
0.057
|
0.906
|
|
| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
GRB2
|
Ubiquitylation
|
K10
|
0.146
|
|
_YDFK(gl)ATADDELSFK_
|
|
GRB2
|
Ubiquitylation
|
K20
|
-0.078
|
|
_ATADDELSFK(gl)R_
|
|
GRB2
|
Ubiquitylation
|
K69
|
-0.362
|
0.641
|
_AK(gl)AEEMLSK_
|
|
GRB2
|
Ubiquitylation
|
K76
|
0.754
|
|
_AEEMLSK(gl)QR_
|
|
GRB2
|
Ubiquitylation
|
K109
|
0.381
|
-0.002
|
_FGNDVQHFK(gl)VLR_
|
|
PLCG1
|
Ubiquitylation
|
K300
|
|
8.031
|
_DLK(gl)NMLSQVNYR_
|
|
PLCG1
|
Ubiquitylation
|
K348
|
|
-0.219
|
_SLMYSAQK(gl)TMDLPFLEASTLR_
|
|
PLCG1
|
Ubiquitylation
|
K552
|
|
-0.355
|
_NMAQYFK(gl)K_
|
|
PLCG1
|
Ubiquitylation
|
K553
|
|
-0.355
|
_NMAQYFK(gl)K_
|
|
PLCG1
|
Ubiquitylation
|
K1063
|
0.864
|
0.355
|
_LTEGK(gl)IMER_
|
|
PLCG1
|
Phosphorylation
|
S1370
|
0.475
|
0.515
|
_AREGS(ph)FESR_
|
|
SOS1
|
Phosphorylation
|
S1082
|
0.278
|
|
_IPESETESTASAPNS(ph)PR_
|
|
SOS1
|
Phosphorylation
|
S1166
|
0.097
|
-0.094
|
_RPESAPAES(ph)SPSK_
|
© Copyright Svejstrup Laboratory 2015