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MDC1-MRN-ATM-FANCD2 complex
(2217)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
FANCD2 5 -0.650 0.520 1.226 0.362 -0.007 1.535 0.808
RAD50 3 0.350 -0.420 0.165 0.571 0.509 0.691 0.587
MDC1 3 0.550 -0.700
NBN 2 -0.220 -0.170 0.708 0.569 -0.563 0.354
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
ATM 0 0.398 0.474

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
FANCD2 Ubiquitylation K77 -0.288 _TGESQNQLAVDQIAFQK(gl)K_
FANCD2 Ubiquitylation K137 0.364 _LQDEEASMGASYSKSLIK(gl)_
FANCD2 Ubiquitylation K322 -0.535 _LQASQVK(gl)LK_
FANCD2 Ubiquitylation K324 -0.384 _LQASQVKLK(gl)_
FANCD2 Ubiquitylation K561 2.102 3.950 _K(gl)QLSSTVFKYK_
FANCD2 Phosphorylation S592 1.311 1.350 _SES(ph)PSLTQER_
FANCD2 Phosphorylation S717 2.435 3.130 _DGGPVTS(ph)QESGQK_
FANCD2 Phosphorylation S1401 -0.015 _S(ph)QNSQESTADESEDDMSSQASK_
FANCD2 Phosphorylation S1404 -0.348 _S(ph)QNSQESTADESEDDMSSQASK_
FANCD2 Phosphorylation S1412 -1.471 _SQNSQESTADES(ph)EDDM(ox)SSQASK_
MDC1 Phosphorylation S168 0.788 0.909 _LLLAEDS(ph)EEEVDFLSER_
MDC1 Phosphorylation S329 -0.069 -0.749 _AQPFGFIDS(ph)DTDAEEERIPATPVVIPMK_
MDC1 Phosphorylation T331 -0.735 -0.646 _AQPFGFIDSDT(ph)DAEEERIPATPVVIPMKK_
MDC1 Phosphorylation S376 -0.196 -0.279 _GPGAPGLAHLQESQAGS(ph)DTDVEEGKAPQAVPLEK_
MDC1 Phosphorylation T378 -0.401 _GPGAPGLAHLQESQAGSDT(ph)DVEEGK_
MDC1 Phosphorylation T404 -0.050 _SQASMVINSDT(ph)DDEEEVSAALTLAHLK_
MDC1 Phosphorylation S453 0.346 _SQTTTERDS(ph)DTDVEEEELPVENR_
MDC1 Phosphorylation T455 -0.574 _SQTTTERDSDT(ph)DVEEEELPVENR_
MDC1 Ubiquitylation K472 -0.332 _EAVLK(gl)DHTK_
MDC1 Ubiquitylation K476 -0.040 _EAVLKDHTK(gl)IR_
MDC1 Phosphorylation S485 0.170 -0.259 _AHS(ph)EKDQPPFGDSDDSVEADK_
MDC1 Phosphorylation S513 3.827 3.443 _S(ph)QASTTVDINTQVEK_
MDC1 Phosphorylation Y775 -0.566 _ESEDSETQPFDTHLEAY(ph)GPCLSPPR_
MDC1 Phosphorylation S780 -0.852 -0.642 _ESEDSETQPFDTHLEAYGPCLS(ph)PPR_
MDC1 Phosphorylation S793 -0.391 -0.332 _AIPGDQHPES(ph)PVHTEPM(ox)GIQGR_
MDC1 Phosphorylation S986 -1.929 _GQASSPTPEPGVGAGDLPGPTSAPVPS(ph)GSQSGGRGSPVSPR_
MDC1 Phosphorylation S995 -0.793 _GQAS(ph)SPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGS(ph)PVSPR_
MDC1 Phosphorylation S1086 1.806 _TRQDGS(ph)QEAPEAPLSSELEPFHPKPK_
MDC1 Phosphorylation T1157 -0.188 _SSVKT(ph)PEPVVPTAPELQPSTSTDQPVTSEPTSQVTR_
MDC1 Phosphorylation S1194 0.770 _S(ph)SVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR_
MDC1 Phosphorylation T1198 0.898 _SSVKT(ph)PETVVPTALELQPSTSTDRPVTSEPTSQATR_
MDC1 Phosphorylation T1239 -1.231 _SSVKT(ph)PEPVVPTAPELQPSTSTDQPVTSEPTYQATR_
MDC1 Phosphorylation T1384 -1.318 _NPESTVPIAPELPPSTSTEQPVT(ph)PEPTSR_
MDC1 Phosphorylation S1399 -0.366 _NRS(ph)SGKTPETLVPTAPK_
MDC1 Phosphorylation S1417 -0.579 _LEPS(ph)TSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation S1419 -0.152 0.059 _LEPSTS(ph)TDQPVTPEPTSQATR_
MDC1 Phosphorylation T1425 0.018 -0.167 _LEPSTSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation T1444 -0.989 _SSVKT(ph)PETVVPTAPELQPSTSTDQPVTPEPTSQATR_
MDC1 Phosphorylation T1466 5.092 _SSVKT(ph)PETVVPTAPELQPSTSTDQPVT(ph)PEPTSQATR_
MDC1 Phosphorylation T1488 -0.511 _SSVKTPET(ph)VVPTAPELQASASTDQPVTSEPTSR_
MDC1 Phosphorylation T1541 -1.076 _TPETVVPAAPELQPST(ph)STDQPVTPEPTSR_
MDC1 Phosphorylation T1548 -1.262 -1.584 _TPETVVPAAPELQPSTSTDQPVT(ph)PEPTSR_
MDC1 Phosphorylation T1567 0.014 0.330 _SSVKT(ph)PESIVPIAPELQPSTSR_
MDC1 Phosphorylation T1589 -0.952 -0.451 _NQLVT(ph)PEPTSR_
MDC1 Phosphorylation T1608 -0.490 -1.272 _SSVKT(ph)PEPVVPTAPEPHPTTSTDQPVTPK_
MDC1 Phosphorylation T1630 -1.705 _SSVKT(ph)PEPVVPTAPEPHPTTSTDQPVT(ph)PK_
MDC1 Phosphorylation T1671 0.063 _TPKPVEPAASDLEPFTPTDQSVT(ph)PEAIAQGGQSK_
MDC1 Phosphorylation S1775 0.591 -0.039 _AAESLTAIPEPAS(ph)PQLLETPIHASQIQK_
MDC1 Phosphorylation S1797 -0.582 -0.634 _S(ph)RFTPELQPK_
MDC1 Phosphorylation T1800 -0.475 -0.235 _SRFT(ph)PELQPK_
MDC1 Phosphorylation S1820 0.073 0.144 _SLATMDS(ph)PPHQK_
MDC1 Ubiquitylation K1885 1.530 _TK(gl)LNQESTAPK_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
NBN Phosphorylation T335 -1.121 _T(ph)TTPGPSLSQGVSVDEK_
NBN Phosphorylation S341 3.085 _TTTPGPS(ph)LSQGVSVDEK_
NBN Phosphorylation S343 3.710 3.629 _TTTPGPSLS(ph)QGVSVDEK_
NBN Phosphorylation S397 2.719 1.458 _MLS(ph)QDAPTVK_
NBN Phosphorylation S432 -0.192 -0.395 _IPNYQLS(ph)PTK_
NBN Phosphorylation T434 -0.188 -0.683 _IPNYQLSPT(ph)KLPSINK_
NBN Phosphorylation S615 1.985 4.691 _IS(ph)QENEIGKK_
RAD50 Ubiquitylation K62 -1.069 _YICTGDFPPGTK(gl)GNTFVHDPK_
RAD50 Phosphorylation S635 2.474 3.050 _LFDVCGS(ph)QDFESDLDR_
RAD50 Ubiquitylation K753 0.394 0.397 _NK(gl)LQNVNR_
RAD50 Ubiquitylation K933 0.397 _FQQEKEELINKK(gl)_
RAD50 Ubiquitylation K1068 0.098 _LEENIDNIK(gl)R_
RAD50 Ubiquitylation K1178 -0.548 _SDADENVSASDK(gl)RR_
RAD50 Ubiquitylation K1285 2.195 _SEYVEK(gl)FYR_


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